Gonzaga and Arizona are heading home and suddenly Kansas is the last No. 1 seed left standing for college basketball betting action ahead of tonight’s Midwest and East region Sweet 16 Matchups.

The No. 1 Jayhawks take on No. 4 Providence tonight, with the Jayhawks -7 favorites. We’ve also got our eyes on No. 4 UCLA as a -2 favorite over No. 8 North Carolina and No. 10 Miami as a -3 favorite over No. 11 Iowa State.

Friday’s College Basketball Betting Lines To Back

Kansas -7 over Providence

We were leaning Providence +7.5 early in the week, but Kansas is available without the hook now and we think it’s a good number for the Jayhawks. The Friars caught a massive break with Richmond taking out Iowa.

To their credit, they took advantage with a 79-51 win. But they caught a few lucky bounces in that game too. Richmond shot just 1 of 22 from 3-point range while Providence went scorched earth and hit 12 of 22 from downtown. That won’t happen against Kansas’ defense. Providence is a strong defensive team that excels on the perimeter, but Kansas isn’t reliant on the 3-point shot.

This is a balanced offensive team that can get to the rack, hitting 19 of 20 free throws in a second-round win over Creighton. Providence could struggle to keep up. We’re on Kansas -7 over Providence.

North Carolina +2.5 over UCLA

While we flipped our first pick from earlier in the week, we’ve been locked in on this one. North Carolina was incredibly impressive in wins over Marquette and No. 1 Baylor. No one seems to know how to handle the Tar Heels’ offense when it’s going like this, scoring 93 points or more in three of the last five games.

They needed overtime to do it against Baylor after blowing a 25-point lead, but we actually think the composure to regroup and drop the hammer in OT is a positive sign moving forward. UCLA will try to slow it down and make it ugly. That’s a tall order tonight. We’re on North Carolina +2.5.

Miami -3 over Iowa State

We can’t trust the Cyclones in this spot. The defense has been very impressive, no doubt. The point totals are alarming. Iowa State has been held under 60 points in four of the last five games, a stretch that includes a 53-36 loss to Oklahoma State and a 72-41 loss to Texas Tech. Credit Iowa State for making it work with tough wins over LSU and Wisconsin, but the 3-point numbers suggest they got away with a couple.

LSU shot just 4 of 19 from deep while the Cyclones were 12 of 37 – yes, they hit 12 threes and still scored just 59 points. The Badgers were even colder than LSU and hit just 2 of 22 from deep. The Hurricanes don’t overly-rely on the three, they have size and they can rip off quick scoring runs at any time. Iowa State is in deep trouble if it falls behind by a few possessions at any point. We’re on Miami -3.

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Buckle up for another loaded weekend of March Madness college basketball betting. The first round did not disappoint, and we’ve got some excellent matchups in store this weekend as these teams look to punch their ticket to the Sweet 16.

For Saturday’s second-round slate, we’re looking at No. 3 Tennessee as a -6.5 favorite over No. 11 Michigan at DraftKings Sportsbook. We’re also watching No. 4 UCLA as a -3 favorite over No. 5 Saint Mary’s, as well as No. 4 Arkansas as a -6.5 favorite over No. 12 New Mexico State.

Saturday's College Basketball Betting Lines To Back

Tennessee -6.5 over Michigan

Michigan showed plenty in a second half comeback win over Colorado State Thursday. Now the Wolverines are in for a much different type of game against a Vols team that plays elite defense and can rip off quick scoring runs at any point. The Wolverines didn’t look nearly sharp enough to compete with a team like this, and they’ll really feel the loss of guard Isaiah Livers today. The Vols could start to run away with this one in the second half, and we’re on Tennessee -6.5.

Saint Mary’s +3 over UCLA

It’s not easy to do what Saint Mary’s did Thursday, blowing out an Indiana team that entered with plenty of momentum after a First Four win over Wyoming. The Gaels played as well as they have all season and proved they belong among the top teams in the nation. UCLA survived a battle with Akron and the Bruins should be concerned. They shot 36.4% from deep, made 11 of 13 free throws, posted a 14-8 assist-turnover ratio and still only beat the Zips by four. The Gaels are one of the few teams in the country that prefer to slow it down even more so than UCLA, so they’re totally comfortable in this matchup. We’re totally comfortable backing them with the points. We’re on Saint Mary’s +3.

Arkansas -6.5 over New Mexico State

The Razorbacks survived a scare against Vermont to advance, while New Mexico State upset UConn, 70-63. It wasn’t your typical upset. The Aggies controlled the game pretty much from start to finish and completely shut down the Huskies’ offense. UConn wasn’t built to come back in games like that, but Arkansas is a different story. The Razorbacks are a senior-led, guard-oriented team with plenty of experience and offensive playmakers. Very few are talking about Arkansas’ potential to make a deep run, but we expect the Razorbacks to impress and handle an Aggies team that’s in trouble given the matchup. We’re on Arkansas -6.5.

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